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Dr. Karen Dannemiller

My interdisciplinary research integrates engineering with microbiology and addresses emerging health challenges and environmental concerns using -omics approaches. Within the indoor environment, we are simultaneously exposed to thousands of chemicals and microorganisms which compose our indoor exposome, and these exposures are different from those of our ancestors.         Broadly, the goal of my work is to understand these exposures, their sources, and their impact on human health. My unique background combines training in both engineering and public health to tackle difficult questions, particularly with regards to exposures in the built environment, where we spend 90% of our time.

I graduated with honors in Chemical and Biochemical Engineering from Brown University and earned my Ph.D. at Yale University in Chemical and Environmental Engineering. During this time, I completed an internship at the California Department of Public Health in the Indoor Air Quality Program. My work improved our understanding of human exposures linked to childhood asthma development and severity. My research also elucidated resident microbial populations and fundamental transport processes occurring in homes. My current research is on microbial activity in house dust and biotransformation of phthalates in homes, and I am excited to tackle new challenges as an assistant professor at Ohio State University.

In addition to a fundamental background in engineering and quantitative sciences, my skill set in microbiology includes phylogenetics, metagenomics, proteomics, and transcriptomics and allows for exploration of microbial communities and biological processes. I have extensive experience with next-generation DNA sequencing of fungi and bacteria and using this data I have also addressed relevant challenges bioinformatics, including software development, and in statistics, to demonstrate complex associations with human health outcomes.

I have also participated in community outreach to disseminate information obtained through research, including presenting a “Science in the News” talk at the New Haven Public Library, volunteering in New Haven schools and with the Yale Pathways program, and judging at the New Haven Science Fair among other activities.

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Ashleigh Bope

I am a graduate student pursuing a Master of Science Degree in the Environmental Science Graduate Program. Previously, I studied at Capital University, where I graduated with honors in Environmental Science and Biology. My research experience has focused on small mammal ecology, exploring the associations between mouse populations and habitat characteristics.
I am very excited to join Dr. Dannemiller in researching the associations between asthma severity and microbial exposures in adult female bedrooms. Using qPCR and DNA sequencing, the fungal, bacterial and viral communities in bedroom dust will be quantified and identified. Statistical analysis will reveal any associations between exposure and sleep disruption. I am also helping to characterize the differences between dPCR and qPCR and the efficiencies associated with indoor dust collection and analysis methods.

Sam Cochran

I am a graduate of The Ohio State University with a B.S. in Biology and a minor in Global Public Health. I am currently getting my masters in Public Health. I work under Dr. Karen Dannemiller, characterizing the accuracy and precision of digital and quantitative PCR utilities, as well as the efficiency in obtaining quantifiable levels of DNA from environmental samples.

 

 

 

Sarah Haines

I am a graduate student pursuing a Masters in Environmental Science. I graduated with Research Distinction in Environmental Engineering in the Spring of 2017 from The Ohio State University. As an undergraduate, I worked with Dr. Karen Dannemiller looking into microbial growth in carpet dust at varying relative humidity conditions. I presented this research and won the poster competition at the NCSE 2017 National Conference and Global Forum on Science, Policy and the Environment in D.C. As a graduate student I am continuing the research I conducted as an undergraduate, upping the samples size and collecting carpet and dust samples from 20 different homes across Ohio. This research will then be used to complete my thesis looking at how microbes in carpet dust react to diurnal variations in relative humidity. 

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Lingyi Xu 

I am an undergraduate student pursuing a B.S in Environmental Engineering at The Ohio State University. I work under Dr. Karen Dannemiller as an undergraduate research assistant, utilizing microscopy to view bacterial and fungal growth in carpet dust. This work will support Sarah Haines’s ongoing research on microbial growth in carpet dust at varying relative humidity conditions. Currently, I utilize different stain under a fluorescent microscope to observe fungal growth and distribution, as well as the distribution of live and dead bacterial on the carpet embedded with dust. 

Alumni

Quentin Platt

 

A graduate of The Ohio State University with a B.S. in Environmental Engineering. Researched the indoor air quality of LEED-certified buildings compared to non LEED buildings. 

 

 

Paige Frey

A graduate of The Ohio State University with a Bachelors in Environmental Engineering.  Aided in creating a smartphone app that will detect the levels formaldehyde in homes and other places with human occupancy.